NEAT1 and neoplasm: Also, a significant link between the presence of the progesterone receptor in the original tumor and the expression of the pluripotency marker NEAT1 in T-47D cells growing in PDSs was observed; where PDSs from PR-positive tumors induced a significant lower expression of this gene (p < 0.001), compared to the PDSs derived from tumors lacking the PR (Figure 3J).