-Compound K exerts an anti-proliferative effect on colon cancer-Compound K actively inhibited the cellular growth of colon cancer-Compound K significantly induced apoptosis-Compound K significantly reduced the production of IL-8 at 20 μM-Compound K exerts significant anti-inflammatory effects on colon cancer at low concentration. This evidence concerns the gene CXCL8 and malignant colon neoplasm.