WFDC2 and ovarian cancer: Regardless of age, the women with ovarian cancer demonstrated significantly higher levels of CA125 (under 50 years: 14 vs. 167 U/mL (p < 0.001) and over 50 years: 11 vs. 257 U/mL (p < 0.001)) and HE4 (under 50 years: 53 vs. 284 pmol/L (p < 0.001) and over 50 years: 68 vs. 314 pmol/L (p < 0.001)), respectively (Table 1).