Lastly, the gene expression signatures included were the 13-gene signature panel—YBX3, CBR3, CXCL10, CLASP1, DCTN1, FNDC3B, WSB2, LRIG1, GRM4, ANXA1, WNK1, HDLBP, and POLR2M [28]; the 8-signature classifier—sex, caveolin-1, CD147, EBV-LMP1, MMP11, p-P70S6K, survivin, and SPARC [23]; the immune signature panel—PD-L1, CD163, CXCR5, and CD117 [24], DLL4 with VEGF expression [25], tumor infiltrating lymphocytes (TILs) [27], and PTP4A2 [29]. The gene discussed is SPARC; the disease is neoplasm.