A classifier was developed to combine gender with the expression of seven genes—EBV-latent membrane protein 1 (EBV-LMP1), CD147 (also known as BSG, an OK blood group antigen), caveolin-1 (also known as CAV1, a scaffolding protein within caveolar membranes), Phospho-p70 S6 Kinase (p-P70S6K), Matrix Metallopeptidase 11 (MMP11),survivin (also known as BIRC5, an apoptotic inhibitor), and Secreted Protein Acidic and Cysteine-Rich (SPARC; a cysteine-rich acidic matrix-associated protein) as prognostic biomarkers for NPC [23]. The gene discussed is CAV1; the disease is nasopharyngeal carcinoma.