F2 and Renal insufficiency: Accordingly, relative contraindications to TACE have relied on the exclusion of patients with hepatic synthetic dysfunction and renal insufficiency, mainly based on laboratory criteria of one or more of the following: an elevation of serum bilirubin, aspartate aminotransferase, alanine aminotransferase, prothrombin time/international normalized ratio (INR), or creatinine level, as well as a decrease in platelet count or albumin [14].