So far, the focus has been on adipocyte-released lipids, since it has been shown that bone metastatic PCa cells uptake FA from adipocytes in the bone marrow through the FABP4, and that this higher FA uptake may contribute to the aerobic glycolysis of PCa cells in an HIF-1α-dependent manner [9]. This evidence concerns the gene FABP4 and posterior cortical atrophy.