Further, our analysis using human PCa patients’ data showcased that the lipidic gene signature found in the in vitro model, involving PPARA, VDR, SLC16A1, GPX1 and PAPSS2, was enough to discriminate metastatic from primary PCa tumors, and was associated with a strong decrease in PCa patients’ survival. The gene discussed is SLC16A1; the disease is posterior cortical atrophy.