KLK3 and neoplasm: In univariate analysis time to first tumor-related event was significantly associated with initial tumor grading (ISUP grade, p = 0.010) and PSA response to aRT (p < 0.001), while time from initial treatment (p = 0.059), age at aRT (p = 0.069) and GTV (p = 0.052) showed a statistical trend.