First, we estimated the promoter region near the H19 gene in pancreatic cancer using ChIP-atlas (http://chip-atlas.org/, accessed on 18 January 2022) [58], and we identified the H3K4me3/H3K27Ac enrichment region that displays an active promoter region upstream of the transcriptional start site (TSS) of H19 (Figure 6A). Here, H19 is linked to familial pancreatic carcinoma.