Several emerging urinary biomarkers with enhanced sensitivity and specificity, such as Kidney Injury Molecule-1 (KIM-1), Neutrophil Gelatinase-Associated Lipocalin (NGAL), N-acetyl beta glucosaminidase (NAG), Interleukin 18 (IL-18), Insulin-like Growth Factor-Binding Protein 7 (IGFBP7) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) are preferably used for the detection of Acute Kidney Injury (AKI) [14]. The gene discussed is IGFBP7; the disease is acute kidney injury.