In glioma, the TAF15|LINC00665/MTF1|YY2/GTSE1 axis inhibits malignant tumor progression [43].TATA-box-binding protein-associated factor 15 (TAF15) is a member of the FET family and plays an important role in regulating mRNA transcription, RNA splicing, and trafficking. The gene discussed is YY2; the disease is central nervous system cancer.