Regarding human cancers, different molecular elements involved in congression are altered at the genetic or protein level in certain cancers that often correlate with tumor grade and progression, including CENP-E overexpression or downregulation, Kif18a overexpression, Kif4a downregulation or overexpression [217,218,219,220,221], among others [7]. The gene discussed is KIF4A; the disease is cancer.