FAP and muscular dystrophy: Our results indicated that, at the cellular and molecular level, LGMD-R12 muscular dystrophy is characterized by the expression of genes indicative of fibroblast and adipocyte replacement, such as fibroadipogenic progenitor (FAP) cells and immune cell infiltration, while gene signatures associated with striated muscle (protein synthesis, OXPHOS, glycogen-, glucose- and amino acid metabolism) are downregulated in dystrophic muscle.