We found that pgc-1α (Figure 4H), which regulates mitochondrial biogenesis [40], and tfam (Figure 4I), which represents mitochondrial DNA levels and is a transcription factor for inducing mitochondrial DNA encoding respiratory molecules [41], were both upregulated in the retina of P23H RP models treated with PBA, suggesting that mitochondrial biogenesis was activated by PBA treatment. This evidence concerns the gene TFAM and retinitis pigmentosa 1.