We found that pgc-1α (Figure 4H), which regulates mitochondrial biogenesis [40], and tfam (Figure 4I), which represents mitochondrial DNA levels and is a transcription factor for inducing mitochondrial DNA encoding respiratory molecules [41], were both upregulated in the retina of P23H RP models treated with PBA, suggesting that mitochondrial biogenesis was activated by PBA treatment. The gene discussed is PPARGC1A; the disease is retinitis pigmentosa 1.