Furthermore, scientists observed a higher amount of M2-associated mRNAs for e.g., IL-10, Arg-1, and TGFβ and the reduction of M1-associated mRNAs such as TNF-α, IL-6, and IL-12 in tumor-associated macrophages from EC specimens, in comparison to macrophages obtained from healthy specimens [100]. Here, IL6 is linked to neoplasm.