KHSRP and age-related macular degeneration: Due to its central role in AMD of pro-inflammatory mediators, KSRP was considered as an important negative regulator of inflammatory immune responses by limiting cytokine production of activated immune cells, since it promoted decay of the according mRNA, as observed in cell culture experiments [22] and when assaying primary cells isolated from KSRP−/− mice [16,69,70,71].