In addition to the reduced number of PMN in KSRP−/− mice, the attenuated course of CAIA in KSRP−/− mice may be explained also by the intrinsic property of KSRP−/− CD4+ T cells to express preferentially Th2-related cytokines such as IL-4, IL-5, IL-10, and IL-13, which have been described to be important for the resolution of RA-associated inflammation in diseased joints [69,70,106]. This evidence concerns the gene KHSRP and rheumatoid arthritis.