BRCA1 and breast cancer: Based on molecular profiling of mammary tumors from mouse models of breast cancer, individual tumors were clustered together on a dendrogram, suggesting that some models (MMTV-neu, MMTV-PyMT, Wap-Myc, and Wap-Int3) showed similar features to the luminal subtype of human breast cancer and that other models (C3(1)-Tag, Wap-Tag, and Brca1-deficient models) were similar to the basal subtype (Table 2).