FASLG and autoimmune hemolytic anemia: This cardinal presentation is associated with mutation of CD95, CD95L, or caspase 10, a defect in lymphocyte proliferation, autoimmune cytopenia (mainly autoimmune hemolytic anemia and immune thrombocytopenic purpura), augmentation of Immunoglobulin A and G titers, associated with elevated dosage of B12 vitamin, augmentation of IL-10 or IL-18 and an increase in soluble-CD95L in patient serum.