In NPC, hypoxic adipocyte-derived EVs reduced the expression of miR-433-3p, resulting in increased levels of stearoyl-CoA desaturase 1 (SCD1), which is the key regulatory gene for the synthesis of monounsaturated fatty acids (MUFAs) and plays an important role in the lipid metabolism of tumors [134]. The gene discussed is SCD; the disease is nasopharyngeal carcinoma.