Higher expression of DJ-1 associated with dysregulated levels of EMT biomarkers, particularly E-cadherin and vimentin, in esophageal squamous cell carcinoma (ESCC) tissue samples has been also reported [16] In human ECA-109 cells in vitro and in the in vivo nude mouse abdominal transplant model, DJ-1 overexpression is strongly associated with proliferation, migration, invasion, and EMT, mainly through the Wnt/β-catenin pathway [16]. The gene discussed is VIM; the disease is esophageal squamous cell carcinoma.