Several studies reported the requirement of DJ-1 for the maintenance of the transformed phenotype (e.g., uncontrolled proliferation, contact inhibition loss, anchorage-independent growth, extracellular matrix invasion) in cancer cells, as well as for the regulation of transformed growth, survival, chemoresistance, and metastasis formation and differentiation [28,29,30,31,32]. Here, PARK7 is linked to cancer.