WIF1 and non-Hodgkin lymphoma: Moreover, a loss of methylation at H3R8me2(arginine residue at position 8 of histone 3) and H4R3me2 (arginine residue at position 3 of histone 4) promoter regions of AXIN2 and Wnt Inhibitory Factor 1 (WIF1) caused by the inhibition of protein arginine methyltransferase 5 (PMRT5) promoted lymphoma cell survival in patient-derived NHL cell lines [70].