For instance, Wei et al. reported that circ-CDYL is upregulated in HCC and is a competing endogenous RNA for miR-328-3p and miR-892a via its interactions with mRNA encoding hypoxia-inducible factor 1-α inhibitor (HIF1AN) and hepatoma-derived growth factor (HDGF). This evidence concerns the gene HIF1AN and hepatocellular carcinoma.