Cdr1as (or CiRS-7) has been shown to be significantly upregulated in cardiomyocytes undergoing either hypoxia treatment or myocardial infarction, where it regulates the expression of SP1 and PARP by sponging miR-7a to promote cardiomyocyte apoptosis [69]. This evidence concerns the gene LINC00632 and myocardial infarction.