CD4 and neoplasm: The increase in CD8+ TRM-like cells with captopril treatment was more substantial in the absence of tumour (Figure 4c; 15.8% vs. 41.9%, control vs. treatment, p < 0.001), compared with that observed in the CLRM model (Figure 2a; 10.3% vs. 18.3%, p = 0.2) and this was also accompanied by a large reduction in the CD4+ TRM-like:CD8+ TRM-like ratio (control 0.47 vs. captopril 0.13, p < 0.001, Table S2).