MGP and chronic kidney disease: For each doubling of plasma decarboxylated matrix protein Gla, the risk of onset of CKD and microalbuminuria was 1.85 [95% confidence interval (CI) 1.59–2.16, respectively; p < 0.001] and 1.19 (95% CI 1.07–1.32; p = 0.001), suggesting a possible prognostic value of dp-ucMGP in CKD, as it could imply a role for poor vitamin K status in the development of chronic renal failure [51].