PTEN and posterior cortical atrophy: To test this hypothesis, we also examined the anti-glycolytic activity of δ-TT (15 μg/mL, 24 h) in PC3 castration-resistant PCa cells, known to be PTEN-deficient and to undergo Akt dephosphorylation-related apoptosis after exposure to the nutraceutical [9,11,17].