TLR4 and rheumatoid arthritis: Other miRNAs such as miR-146a [74], miR-766-3p [75] and miR-548a-3p [76] mediate the proliferation and inflammation of RA fibroblast-like synoviocytes by downregulating Toll-like receptors/the nuclear factor-κB (TLR4/NF-κB) signaling pathway.