More specifically, it was shown that the augmentation of autologous SCT with autologous lymphocyte infusions, combined with immunotherapeutic products containing recombinant MAGE-A3 protein, is able to generate a robust MAGE-A3-specific CD4+ T cell immune response, highlighting that the period around graft re-infusion provides a favorable milieu for additional immunotherapy, including tumor-antigen vaccination [71]. This evidence concerns the gene MAGEA3 and neoplasm.