In preliminary experiments, we also observed an increased angiogenesis associated with a more rapid in vivo growth of B16F10 melanoma cells transfected with sense VEGF genes (B16F10SVm) relative to the parental B16F10 tumor cells transfected with a control vector (B16F10pEF) in C57BL/6N mice (Table S1). The gene discussed is VEGFA; the disease is neoplasm.