Finally, the glycosylation profiles corresponding to anti-PR3 specific IgG1 and total IgG1 in patients with GPA were found to be similar; however, the total galactosylation and sialylation of IgG1 were found to be weakly or not correlated with their anti-PR3 specific IgG1 counterparts, respectively. This evidence concerns the gene PRTN3 and granulomatosis with polyangiitis.