TP53 and renal pelvis/ureter urothelial carcinoma: Regarding the comparison of UTUC metachronous and bladder primary MIBC, significantly higher rates of intermix of both FGFR3 and p53 expression were observed in UTUC metachronous MIBC (primary bladder MIBC: 12.0% vs. UTUC metachronous MIBC: 50.0%; Figure 4b).