With regard to inflammation, nuclear paraspeckle assembly transcript 1 (NEAT1) has been proposed as a candidate lncRNA involved in the attenuation of inflammation, as its overexpression is strongly associated with reduced TNF-α-induced vascular cell pro-inflammatory response and it has been found to be upregulated in peripheral blood mononuclear cells (PBMCs) from patients with CAD and in carotid artery atherosclerotic plaques [117]. This evidence concerns the gene NEAT1 and coronary artery disorder.