NT5E and non-small cell lung carcinoma: T-cell proliferation was significantly reduced in the presence of conditioned medium derived by NSCLC CSC spheres alone or co-cultured with OCs compared to the control, p < 0.05, Figure 4C. Supernatants from NSCLC CSC spheres treated with both APCP (p < 0.01) and the anti-CD73 moAb (p < 0.05) resulted in inhibition of T-cell proliferation.