It should be noted that other misfolded and aggregated pathogenic proteins associated with neurodegenerative diseases, such as Aβ for AD, TDP-43 and SOD1 for ALS, and α-synuclein for Parkinson’s disease, are also proposed to spread in a prion-like manner along neural connections [160,161]. Here, TARDBP is linked to amyotrophic lateral sclerosis.