The Mgat5−/−:Npc1−/− mice (n = 17) developed an NPC disease phenotype similar to that of Mgat5+/+:Npc1−/− mice (n = 11) (Figure 1C) when assessed weekly for grooming, motor function, kyphosis, hindlimb clasp, and ledge test. The gene discussed is MGAT5; the disease is nasopharyngeal carcinoma.