The nucleotide-binding oligomerization domain leucine-rich repeat and pyrin domain-containing protein 3 (NLRP3) inflammasome, one of the most well-studied inflammasomes, plays a crucial role in neurodegenerative diseases, recognizing a variety of inflammation-inducing stimuli, such as damage-associated molecular patterns (DAMPs) or pathogen-associated molecular patterns (PAMPs), leading to the production of proinflammatory cytokines IL-1 and IL-18 [8]. This evidence concerns the gene NLRP3 and neurodegenerative disease.