ARRDC2 has been identified as one of the genes upregulated in human lung epithelial cells upon infection with respiratory syncytial virus [161], and a recent study based on machine learning proposed the ARRDC2 gene as a potential target of the miRNA of the human endogenous retrovirus K-113 [162], which is often upregulated in breast cancer [163]. The gene discussed is ARRDC2; the disease is infection.