TUDCA, an ER stress inhibitor, alleviated steatotic allograft injury and inflammation in rat livers and also inhibited the activation of the caspase-11 non-canonical inflammasome and IL-1β production [39], suggesting that ER stress and the activation of the caspase-11 non-canonical inflammasome in the liver play a critical role in steatotic allograft-induced liver inflammation and injury. Here, IL1B is linked to inflammatory response.