Steatotic allograft increased endoplasmic reticulum (ER) stress, which led to liver inflammation and injury in rats, and these steatotic allograft-induced liver inflammations and injuries were mediated by the activation of the caspase-11 non-canonical inflammasome and caspase-11 non-canonical inflammasome-induced IL-1β production [39]. This evidence concerns the gene IL1B and inflammatory response.