However, when Sciascia et al. compared the aPL profile (criteria aPL and aPS/PT IgG and IgM) of 87 COVID-19 patients with APS patients and with patients with acute infections (excluding SARS-CoV2), they found that the aPL profile in COVID-19 patients differed from that of APS patients but was similar to those suffering from other infections [62]. The gene discussed is CD40LG; the disease is infection.