IFNG and breast angiosarcoma: DNA hypomethylation (e.g., LINE-1, ALU, and SAT2 repetitive sequences and IFNγ promoter) triggers IFN-γ-induced epithelial injury in BA infants, which is associated with overexpression of miR-29b and miR-142-5p, causing the downregulation of DNMT1 and DNMT3a/b (Figure 3) [81].