As TGF-β1 is a key facilitator of the EMT transition by switching cellular energy provision from oxidative phosphorylation to substrate-level phosphorylation through aerobic glycolysis [182], the reduction of high glycolytic fluxes with 2-deoxyglucose could reduce peritoneal fibrosis [183,184]. This evidence concerns the gene TGFB1 and Peritoneal Fibrosis.