Post-hoc comparisons further confirmed a significant stroke-induced upregulation in GFAP+ve expression within the PI region of vehicle- (497,644 ± 97,301; p < 0.0001) and compound A-treated stroke animals (465,055 ±196,949; p < 0.0001), relative to saline-treated shams (99,728 ± 46,939). The gene discussed is GFAP; the disease is stroke disorder.