The functional enrichment analysis of the 30 genes upregulated (FDR < 0.05, FC > 2) in both these datasets indicated functional categories including “TNFα signaling via NFKB”, “hypoxia”, “apoptosis”, “late estrogen response” and “wounding responses” (Figure 2E), suggesting that these endometrial pathways may be central in promoting adenomyosis development. The gene discussed is TNF; the disease is adenomyosis.