We next compared the transcriptional changes in the HSD17B1TG uterus to those describing changes in eutopic endometrium in human adenomyosis patients [21], in mice treated with E2 [22] and in stromal cell cultures treated with siRNA against progestin receptor (PGR) [23], using gene set enrichment analysis (GSEA). This evidence concerns the gene PGR and adenomyosis.