In the phase 3 study of “Bezafibrate in Combination with Ursodeoxycholic Acid in Primary Biliary Cirrhosis (BEZURSO; NCT01654731)” completed in December 2016, its dual actions on PPARα/δ were considered important for the improvement of biochemical measures, such as liver stiffness [31]. The gene discussed is PPARA; the disease is primary biliary cholangitis.