In contrast, miR-485-3p promoted AD severity by targeting AKT3, a gene regulating cell proliferation, apoptosis, and inflammatory response, in Aβ40-treated SH-SY5Y and BV2 cells, positively correlating with the inflammatory response triggered by IL-1β, IL-6, and TNF-α [58]. This evidence concerns the gene IL6 and Alzheimer disease.