B16F10 cells were used to assess uptake and photodynamic cytotoxicity.BMDCs were used to assess maturation (measured as expression of CD80, CD86, and CD40 and secretion of cytokines IL-6, IL-12/p70, and TNF-α).C57BL/6 mice bearing B16F10 tumours were used to assess biodistribution and anticancer effects of the nanoformulation intravenously injected 8 days after tumour inoculation. The gene discussed is CD40; the disease is neoplasm.