KEGG pathways for the hypoxia brain citrullinome relating to hemostasis and immunological/inflammatory pathways included platelet activation, apelin signalling pathway, human T-cell leukemia virus 1 infection, hepatitis B, chemokine signalling pathway, apoptosis, inflammatory mediator regulation of TRP channels, cellular senescence, renal cell carcinoma, and MAPK signalling pathway. The gene discussed is APLN; the disease is hepatitis B virus infection.