P2RX7 and infectious otitis media: At the phylum level, compared to the P2X7+/+ control group, the AOM/DSS-induced P2X7R+/+ group presented a trend toward a higher relative abundance of Firmicutes (4–20% vs. 13–31%) and Tenericutes (0–0.4% vs. 0.1–1.4%), whereas Fusobacterium was exclusively identified in the AOM/DSS-induced P2X7R+/+ group (Figure 7D).