For example, a recent report suggests that the chemokine CX3CL1 promotes lung cancer invasion and migration by elevating the levels of c-Src and c-Abl to increase CTTN phosphorylation, since inhibition of src/abl, or mutating the phosphorylation sites in CTTN, blocks lung cancer invasion and migration [138]. The gene discussed is ABL1; the disease is lung carcinoma.