Another study correlated immunohistochemistry and clinical data to demonstrate that CTTN (and SIRT1) expression is significantly increased in non-small cell lung cancers (NSCLC), and it is associated with high pathological lymph node metastasis, tumor invasion, and shorter survival, which suggests a potential role for CTTN in NSCLC progression [62]. Here, SIRT1 is linked to non-small cell lung carcinoma.