GHRL and Parkinson disease: An early investigation, which employed a subacute MPTP-precipitated experimental model of mouse with PD, has indicated that the nerve cell protective outcomes of ghrelin may be strongly associated with a substantial plummet in the caspase-3-elicited programmed cell death through the modulation of the expression of the two, namely Bax and Bcl-2, within the DA-forming nerve cells of the nigral region of the encephalon [130].