BCL2 and neuroblastoma: Moreover, Dpr3ghr, an analog of ghrelin, has been reported to safeguard human neuroblastoma (SH-SY5Y) cells (by escalating the expression of B-cell lymphoma-2 (Bcl-2), and de-escalating the Bcl-2-associated X protein (Bax) expression and Bax/Bcl-2 ratio) from the enormously perilous two carbonyl (C=O) groups comprising the organic compound, possessing the molecular formula CH3C(O)CHO, namely methylglyoxal (MGO)-precipitated programmed cell death and nerve cell toxicity [149].