SQSTM1 and Parkinson disease: A recent exploration has demonstrated that PACAP therapy considerably plummeted the autophagic operation in MPTP-provoked experimental PD models via regulating the concentrations of a protein termed sequestosome-1/p62, and by carrying out the formation of microtubule-associated protein light chain 3-phosphatidylethanolamine conjugate (LC3-II) [195].