In accordance with another investigation, microglia stimulation was noticed inside the SN of PD-experiencing individuals, inevitably culminating in the liberation of proinflammatory molecules, encompassing interferons (IFNs), tumor necrosis factor-alpha (TNF-α), and interleukins (ILs), which, as a consequence, contributes to apoptosis in PD [59,100]. Here, TNF is linked to Parkinson disease.