CXCL16 and cholangiocarcinoma: However, if the analysis was confined to the group of CC patients that expressed high levels of CXCL16 mRNA (i.e., CXCL16 mRNA values >7.2 copies/18S rRNA unit; [14]) it was found that the patients in the GPR55(+) group (n = 33) had 0.3- and 0.4-fold decreased recurrence rates compared to the low-expression group (GPR55(−) group, n = 15) when followed for 5 and 12 years after surgery, respectively (p = 0.02 and p = 0.04).