EGFR and metastatic malignant neoplasm in the lymph nodes: Considering a series of 30 TBSCCs, Morita et al. [19] discovered that both p53 and EGFR nuclear and membranous immunohistochemical expression in neoplastic cells was significantly associated with T classification, whereas EGFR expression alone was significantly more frequent in patients with lymph node metastasis compared to those without node involvement.